The Art Institute of New York City occupies approximately 50,000 square feet of space at 75 Varick Street and 58,000 square feet at 11 Beach Street in the SoHo/TriBeCa district of New York City.

Students have access to a lounge and changing rooms. The Education Department, Human Resources and Public Relations are also situated at the Varick location, as are library resources, facilities, and services which are shared with Metropolitan College.

The Beach Street location, two-and-a half blocks from Varick, houses the Graphic Design, Web Design & Interactive Media, Video Production, Interior Design, and Fashion Design departments. There are 13 classrooms, 5 computer labs (3 Mac and 2 PC), and 2 drawing studios, one for life drawing. A large bookstore and an art gallery are located on the first floor.

All lecture classes are housed at the Beach Street site, many in classrooms equipped with TV monitors, VCRs and overhead projectors. The maximum number of students in a class is 36 students per lecture and 25 students per computer lab.